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Abstract
Objective: To study the characteristics of fatigue and related factors in patients diagnosed with major depressive disorder treated at the Institue of Mental Health in 2025.
Methods: A cross-sectional despriptive study was conducted on 77 inpatients diagnosed with major depressive disorder and hospitalized at National Institue of Mental Health from May 2025 to November 2025. The data were collected through direct interviews with patients using a structured questionnaire consisting of four scales: FAsD-V2, PHQ-9, Morisky, and SF-36.
Results: A total of 77 inpatients, fatigue was highly prevalent, reported by 100% of participants, with moderate fatigue being the most common (48.1%). It frequently appeared concurrently with depressive symptoms (49.4%), persisted throughout the day (51.9%), was often worse in the morning, and showed limited improvement after rest (53.2%). Factors significantly associated with fatigue severity included married status, sleep duration, depression severity, medication adherence, and quality of life( p < 0.05).
Conclusions: These findings highlight that fatigue is a multidimensional, persistent symptom affecting the quality of life. Early detection and integrated management of fatigue should be prioritized as key therapeutic targets in major depressive disorder.
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References
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