Abstract
Objective: To determine the prevalence of geriatric syndromes and their association with age among older adults attending the Department of Geriatrics – Health Protection, Thai Nguyen National Hospital. Subjects and
Methods: A cross-sectional descriptive study was conducted on 475 older patients. Data were collected through face-to-face interviews and medical records using validated instruments, including the Katz Activities of Daily Living (ADL) index, Lawton Instrumental Activities of Daily Living (IADL) scale, SARC-F questionnaire, 21-item Fall Risk Index (Fri-21), Mini-Mental State Examination (MMSE), Edmonton Frail Scale (EFS), and 15-item Geriatric Depression Scale (GDS-15) and analysed using SPSS 25.0, applying the Chi-square test and univariable logistic regression.
Results: Mean age was 76.83 ± 6.89 years. Most participants were aged ≥70 years, and females outnumbered males. The prevalence of geriatric syndromes was as follows: multimorbidity (67.4%), polypharmacy (66.7%), sarcopenia (44.8%), IADL impairment (46.5%), cognitive impairment (47.4%), frailty (36.8%), ADL impairment (36.6%), high risk of falls (33.1%), and depression (26.5%). Univariate logistic regression analysis showed that, compared with the 60–69 age group, those aged ≥80 had significantly higher odds of polypharmacy, frailty, sarcopenia, and multimorbidity, while in the 70–79 group only polypharmacy was significantly associated with age (OR 1.88 vs. 2.49 for the ≥80 group).
Conclusion: Geriatric syndromes are highly prevalent among older adults. Comprehensive geriatric screening should be strengthened, especially for medication use, sarcopenia, and frailty in patients aged ≥ 80 years to enable timely and appropriate interventions.
Keywords
References
General Statistics Office of Vietnam. Press Release: Results of the 2024 Mid-Term Population and Housing Census. Accessed September 24, 2026. https://www.nso.gov.vn/du-lieu-va-so-lieu-thong-ke/2025/01/thong-cao-bao-chi-ket-qua-dieu-tra-dan-so-va-nha-o-giua-ky-nam-2024/
Inouye SK, Studenski S, Tinetti ME, Kuchel GA. Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept. J Am Geriatr Soc. 2007;55(5):780-791. doi:10.1111/j.1532-5415.2007.01156.x
Tran LV, Nguyen TX, Nguyen TTH, et al. Prevalence of Geriatric Syndromes among Older Outpatients with Dementia. Dement Geriatr Cogn Disord Extra. 2024;14(1):89-95. doi:10.1159/000541237
Vu HTT, Nguyen TTH, Le TA, et al. Comprehensive Geriatric Assessment in Older Patients with Diabetes Mellitus in Hanoi, Vietnam. Gerontology. 2022;68(10):1132-1138. doi:10.1159/000521601
Nicholson K, Liu W, Fitzpatrick D, et al. Prevalence of multimorbidity and polypharmacy among adults and older adults: a systematic review. Lancet Healthy Longev. 2024;5(4):e287-e296. doi:10.1016/S2666-7568(24)00007-2
Nguyen NTY, Le TL, Tran TN, Nguyen TPA, Nguyen DPA. Polypharmacy and frailty among hospitalized older patients in Vietnam. J 108 - Clin Med Phamarcy. Published online May 15, 2026. doi:10.52389/ydls.v21i4.3009
Mielke N, Barghouth MH, Fietz AK, et al. Effect modification of polypharmacy on incident frailty by chronic kidney disease in older adults. BMC Geriatr. 2024;24(1):335. doi:10.1186/s12877-024-04887-5
Tran VL, Nguyen NT, Nguyen TTH. Geriatric syndromes and their association with nutritional status in older patients with mild cognitive impairment. Vietnam Medical Journal. 2024;535(1B). doi:10.51298/vmj.v535i1B.8395
Zhai B, Liu X, Fu J, Zhu X, Li J. More cognitive gains from social activity in the oldest-old: evidence from a 10-year longitudinal study. Front Psychol. 2024;15. doi:10.3389/fpsyg.2024.1382141
Nguyen QA, Nguyen TX, Pham T, Tran VL. Multimorbidity among older adults at Nghe An Friendship General Hospital. Vietnam Medical Journal. 2023;529(1). doi:10.51298/vmj.v529i1.6288
Masnoon N, Shakib S, Kalisch-Ellett L, Caughey GE. What is polypharmacy? A systematic review of definitions. BMC Geriatr. 2017;17(1):230. doi:10.1186/s12877-017-0621-2
Johnston MC, Crilly M, Black C, Prescott GJ, Mercer SW. Defining and measuring multimorbidity: a systematic review of systematic reviews. Eur J Public Health. 2019;29(1):182-189. doi:10.1093/eurpub/cky098
Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of Illness in the Aged: The Index of ADL: A Standardized Measure of Biological and Psychosocial Function. JAMA. 1963;185(12):914-919. doi:10.1001/jama.1963.03060120024016
Lawton MP, Brody EM. Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living. The Gerontologist. 1969;9(3 Part 1):179-186. doi:10.1093/geront/9.3_Part_1.179
Wada T, Ishimoto Y, Hirosaki M, et al. Twenty-one-item fall risk index predicts falls in elderly community-dwelling japanese. J Am Geriatr Soc. 2009;57(12):2369-2371. doi:10.1111/j.1532-5415.2009.02591.x
Dinh HT, Ha L vu H, Luu NM, et al. Frailty as a Predictor of Falls in Older Adults with Type 2 Diabetes: Evidence from Vietnam. Clin Interv Aging. 2025;20:2641-2650. doi:10.2147/CIA.S560920
Cao ML, Ho TKT, Tran KT. The value of the Mini-Mental State Examination (MMSE) for screening dementia among older adults in the community. Journal of Medical Research. 2022;149(1):229-236. doi:10.52852/tcncyh.v149i1.525
Rolfson DB, Majumdar SR, Tsuyuki RT, Tahir A, Rockwood K. Validity and reliability of the Edmonton Frail Scale. Age Ageing. 2006;35(5):526-529. doi:10.1093/ageing/afl041
Vu HTT, Nguyen TX, Nguyen TN, et al. Prevalence of frailty and its associated factors in older hospitalised patients in Vietnam. BMC Geriatr. 2017;17(1):216. doi:10.1186/s12877-017-0609-y
Nguyen TTT, Quach TH, Nguyen TMN, Nguyen TTB. Validation of the Vietnamese version of the Geriatric Depression Scale-15 short form for screening depression in older adults. Journal of Health Sciences. 2024;2(2):65-65. doi:10.59070//jhs020224018
Tn N, At N, Lq K, et al. Reliability and Validity of SARC-F Questionnaire to Assess Sarcopenia Among Vietnamese Geriatric Patients. Clin Interv Aging. 2020;15. doi:10.2147/CIA.S254397
Daimaru K, Osuka Y, Kojima N, et al. Associations of polypharmacy with frailty severity and each frailty phenotype in community-dwelling older adults: Itabashi Longitudinal Study on Aging. Geriatr Gerontol Int. 2024;24 Suppl 1:196-201. doi:10.1111/ggi.14789
Liu Y, Zhang L, Li X, et al. Prevalence and risk factors of frailty in older adults with diabetes: A systematic review and meta-analysis. PloS One. 2024;19(10):e0309837. doi:10.1371/journal.pone.0309837
Prokopidis K, Giannos P, Reginster JY, et al. Sarcopenia is associated with a greater risk of polypharmacy and number of medications: a systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2023;14(2):671-683. doi:10.1002/jcsm.13190

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright (c) 2026 Journal of Nursing Science